Tag Archives: estriol
Estriol and Breast Cancer

Over the past few years controversy has erupted over the risk of developing breast cancer with estriol therapy. A study from Sweden (Rosenberg et al, 2006) suggests that estriol can increase risk of lobular carcinoma when used for five years or less, and decrease the risk when used for more than five years. Unlike estriol however, oral estradiol and progestins continue to increase risk after five years. The results of this study may appear to be confusing, but can be explained by the differences in cancer initiation and cancer promotion by different types of estrogen.
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